Investigador responsable: Rafael Gabriel Sánchez
Entidad: Instituto de Salud Carlos III
Investigadores:
Kozakova M, Palombo C, Paterni Eng M, Dekker J, Flyvbjerg A, Mitrakou A, Gastaldelli A, Gabriel R, , Ferrannini E; RISC Investigators. Fatty liver index, gamma-glutamyltransferase, and early carotid plaques. Hepatology. 2012. May;55 (5):1406-15. TP: A. FI: 12.003
Lorenz MW, Price JF, Robertson C, Bots ML, Polak JF, Poppert H, Kavousi M, Dörr M, Stensland E, Ducimetiere P, Ronkainen K, Kiechl S, Sitzer M, Rundek T, Lind L, Liu J, Bergström G, Grigore L, Bokemark L, Friera A, Yanez D, Bickel H, Ikram MA, Völzke H, Johnsen SH, Empana JP, Tuomainen TP, Willeit P, Steinmetz H, Desvarieux M, Xie W, Schmidt C, Norata GD, Suarez C, Sander D, Hofman A, Schminke U, Mathiesen E, Plichart M, Kauhanen J, Willeit J, Sacco RL, McLachlan S, Zhao D, Fagerberg B, Catapano AL, Gabriel R, Franco OH, Bülbül A, Scheckenbach F, Pflug A, Gao L, Thompson SG. Carotid Intima Media Thickness Progression and Risk of Vascular Events in People With Diabetes: Results From the PROG-IMT Collaboration. Diabetes Care. 2015 Oct;38(10):1921-9.TP: A. F.I: 8.420
Mari A, Tura A, Natali A, Anderwald C, Balkau B, Lalic N, Walker M, Gabriel R, Ferrannini E; RISC Investigators. Influence of hyperinsulinemia and insulin resistance on in vivo β-cell function: their role in human β-cell dysfunction. Diabetes. 2011 Dec;60(12):3141-7. TP: A. IF: 8.889.
Pilz S, Rutters F, Nijpels G, Stehouwer CD, Højlund K, Nolan JJ, Balkau B, Gabriel R, Dekker JM; RISC Investigators. Response to Comment on Pilz et al. Insulin sensitivity and albuminuria: the RISC study. Diabetes Care 2014;37:1597-1603. Diabetes Care. 2015 Feb;38(2):e31. FI: 8.420
Pilz S, Rutters F, Nijpels G, Stehouwer CD, Højlund K, Nolan JJ, Gabriel R, Balkau B, Dekker JM; RISC Investigators. Insulin sensitivity and albuminuria: the RISC study. Diabetes Care. 2014 Jun;37(6):1597-603. doi: 10.2337/dc13-2573. Epub 2014 Mar 12. PMID: 24623021. FI: 8.420
Jaakko Tuomulehto:
Participación como autor en consorcios internacionales de genética:
Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015 Feb 12;518(7538):197-206. doi: 10.1038/nature14177. PubMed PMID: 25673413. FI: 41.456
Directional dominance on stature and cognition in diverse human populations. Nature. 2015 Jul 23;523(7561):459-62. FI: 41.456
Otros temas:
Ngandu T, Lehtisalo J, Solomon A, Levälahti E, Ahtiluoto S, Antikainen R, Bäckman L, Hänninen T, Jula A, Laatikainen T, Lindström J, Mangialasche F, Paajanen T, Pajala S, Peltonen M, Rauramaa R, Stigsdotter-Neely A, Strandberg T, Tuomilehto J, Soininen H, Kivipelto M. A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial. Lancet. 2015 6;385(9984):2255-63 FI: 45.217
Yates T, Haffner SM, Schulte PJ, Thomas L, Huffman KM, Bales CW, Califf RM, Holman RR, McMurray JJ, Bethel MA, Tuomilehto J, Davies MJ, Kraus WE. Association between change in daily ambulatory activity and cardiovascular events in people with impaired glucose tolerance (NAVIGATOR trial): a cohort analysis. Lancet. 2014 Mar 22;383(9922):1059-66. doi: 10.1016/S0140-6736(13)62061-9. FI: 45.217
Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, Lee H, Oskolkov N, Fadista J, Ehlers K, Wahl S, Hoffmann C, Qian K, Rönn T, Riess H, Müller-Nurasyid M, Bretschneider N, Schroeder T, Skurk T, Horsthemke B; DIAGRAM+Consortium, Spieler D, Klingenspor M, Seifert M, Kern MJ, Mejhert N, Dahlman I, Hansson O, Hauck SM, Blüher M, Arner P, Groop L, Illig T, Suhre K, Hsu YH, Mellgren G, Hauner H, Laumen H. Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms. Cell. 2014 Jan 16;156(1-2):343-58. FI: 32.242
Metodología de trabajos de campo:
Metodología de análisis estadístico:
Los disponibles en el IIS-Princesa para el desarrollo de los estudios mencionados